Pitomnik was captured by the German 6th Army when it linked up there with the 4th Panzer Army on 3 September 1942.

The airfield at Pitomnik was one of seven airfields within the Stalingrad Pocket after the 6th Army was encircled and the only one properly equipped to handle large amounts of air traffic. The field was equipped with lights for night operation.

Ordered to the "cauldron" by Paulus, Wilhelm Adam flew from Morozovsk airstrip to Pitomnik on 12 Dec. 1942. After his He 111 landed, Adam noted, "The place was overflowing with crashed aircraft and destroyed vehicles: there a 'Condor', here a 'Focke Wulf'. Among the wrecks were several Ju 52s and He 111s – the work of the Red bombers and fighters!"

Along with anti aircraft guns, the airfield was protected by fighter planes of Jagdgeschwader 3, elements of which were based there (the remainder of JG 3 was stationed outside the pocket). In mid-January, the remaining planes of the group were ordered to leave the pocket.

The airfield was used to fly out the remaining female hospital staff of the 6th Army, when the hopelessness of the situation became apparent. Male medical staff were not permitted to leave. The edges of the runway were filled with wounded German soldiers whose conditions were deemed not serious enough for evacuation, and only ambulatory cases were actually evacuated by air.

From 15 January, Pitomnik came under artillery fire of the Red Army and two days later, the airfield was captured, leaving the 6th Army with Gumrak as its only supply airfield. Karpovka had already fallen on 13 January and alongside Pitomnik, four other airfields fell on 17 January. Gumrak eventually fell on 23 January, leaving the 6th Army without any means of direct support.

As of 2009, the location of the Pitomnik Airfield is used as farmland.